Evaluation of ColdZyme Mouth Spray against common cold in preschool staff

Open-label, observational study during 6 months, winter season, (Oct-Mar).

15 adult preschool staff members at a single school.

According to instructions for use.

Officially registered number of sick-days compared to the same period previous year.

A single preschool, Skåne, Sweden

• The specific conditions of preschools (kindergarten) are conducive for transmitting infectious agents. An infected child may easily propagate the virus among adult workers, parents or other contacts.
• Consequences for infected staff often include reduced working capacity and absence from work.

• We observed that when ColdZyme® Mouth Spray was used to reduce common cold viral infections the number of registered sick-days decreased.
• The average number of sick-days decreased from 7.4 to 4.1 days for the 6-month period, compared to previous year.
• The average sick-leave decreased by 3.3 days (p = 0.04).

• It can be concluded that applying a barrier to the pharyngeal mucous membrane is an easy and practical method to reduce transmissions of common cold viruses, and corresponding sick leave in personnel from the preschool environment.
• Use of ColdZyme® could also be beneficial to the economy and society as a whole due to the potential reduction in sick leave and associated costs.